Systematic Review & Meta-analysis of Interventional Randomized Clinical Trials

One study can never be enough to provide an adequate evidence. Systematic review does not simply summarize the results of the previous studies, but it analyze the evidence provided by each study to draw meaningful and statistically valid conclusion (Meta-analysis). Each year the number of published systematic review & meta-analysis is increased reaching up to 28,959 systematic review & 9,135 meta-analysis by 2014. However, with the increased number of published studies comes the risk of low quality studies which creates a threat on implementing the results of these studies in daily practice. Thus, knowing how to conduct & how to assess the quality of systemic reviews & meta-analysis is essential for proper evidence based medical practice.

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